|
Age at menarche
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
Alzheimer's Disease
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
|
23535033 |
2014 |
|
Alzheimer's Disease
|
0.100 |
GeneticVariation
|
disease |
GWASDB |
Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
|
23535033 |
2014 |
|
Autoimmune Diseases
|
0.010 |
GeneticVariation
|
group |
BEFREE |
Further studies of a larger cohort of GW/P body positive patients and structure-function relationships of the variant TNRC6A are required to fully understand the role that such SNPs play in GW/P body autoantibody production and/or pathogenesis of related autoimmune diseases.
|
23224974 |
2013 |
|
Benign adult familial myoclonic epilepsy
|
0.010 |
Biomarker
|
disease |
BEFREE |
Intriguingly, in two families with a clinical diagnosis of BAFME in which no repeat expansions in SAMD12 were observed, we identified similar expansions of TTTCA and TTTTA repeats in introns of TNRC6A and RAPGEF2, indicating that expansions of the same repeat motifs are involved in the pathogenesis of BAFME regardless of the genes in which the expanded repeats are located.
|
29507423 |
2018 |
|
Benign Infantile Myoclonic Epilepsy
|
0.300 |
Biomarker
|
disease |
CTD_human |
Expansions of intronic TTTCA and TTTTA repeats in benign adult familial myoclonic epilepsy.
|
29507423 |
2018 |
|
Blood Pressure
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genetic overlap of chronic obstructive pulmonary disease and cardiovascular disease-related traits: a large-scale genome-wide cross-trait analysis.
|
30940143 |
2019 |
|
Body Height
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
Body mass index
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
Body mass index
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.
|
30239722 |
2019 |
|
Breast Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
To discern further RISC functions, we analyzed the activities of two RISC proteins, AGO2 and GW182, in the MCF-7 human breast cancer cell line.
|
30999843 |
2019 |
|
Cannabis use
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Severity of symptoms, cannabis use and genotype were assessed at baseline in 147 help-seeking young adults who met the ARMS criteria and agreed to participate in the Dutch Early Detection and Intervention (EDIE-NL) trial.
|
27052366 |
2016 |
|
Carcinogenesis
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
The increased expressions of Ago2 and TNRC6A in both PCA and ESCC compared with their normal cells suggested that over-expression of these proteins may be related to miRNA functions and might play a role in tumorigenesis of PCA and ESCC.
|
20402672 |
2010 |
|
Chronic Obstructive Airway Disease
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genetic overlap of chronic obstructive pulmonary disease and cardiovascular disease-related traits: a large-scale genome-wide cross-trait analysis.
|
30940143 |
2019 |
|
Colorectal Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
In cancers with MSI-H, loss of Ago2 expression was observed in 40% of GCs and 35% of CRCs, while loss of TNRC6A was observed in 52% of the GCs and 54% of the CRCs.
|
20198652 |
2010 |
|
Early Childhood Epilepsy, Myoclonic
|
0.300 |
Biomarker
|
disease |
CTD_human |
Expansions of intronic TTTCA and TTTTA repeats in benign adult familial myoclonic epilepsy.
|
29507423 |
2018 |
|
Epilepsy, Myoclonic, Infantile
|
0.300 |
Biomarker
|
disease |
CTD_human |
Expansions of intronic TTTCA and TTTTA repeats in benign adult familial myoclonic epilepsy.
|
29507423 |
2018 |
|
Familial (FPAH)
|
0.010 |
PosttranslationalModification
|
disease |
BEFREE |
The aim was to investigate whether abnormal TTTTA and TTTCA repeat expansions in introns of SAMD12, TNRC6A and RAPGEF2 are involved in the pathogenesis of familial cortical myoclonic tremor with epilepsy (FCMTE).
|
30351492 |
2019 |
|
Hepatitis C
|
0.010 |
Biomarker
|
disease |
BEFREE |
TNRC6 proteins modulate hepatitis C virus replication by spatially regulating the binding of miR-122/Ago2 complexes to viral RNA.
|
30997501 |
2019 |
|
Idiopathic Myoclonic Epilepsy
|
0.300 |
Biomarker
|
disease |
CTD_human |
Expansions of intronic TTTCA and TTTTA repeats in benign adult familial myoclonic epilepsy.
|
29507423 |
2018 |
|
Infantile Severe Myoclonic Epilepsy
|
0.300 |
Biomarker
|
disease |
CTD_human |
Expansions of intronic TTTCA and TTTTA repeats in benign adult familial myoclonic epilepsy.
|
29507423 |
2018 |
|
Intelligence
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.
|
29942086 |
2018 |
|
Intelligence
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.
|
29326435 |
2019 |
|
Intelligence
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.
|
29844566 |
2018 |
|
Kaposi Sarcoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Here, we report the important roles of GW182 and DDX6, but not Dicer, Ago2 and DCP1A, in PB formation, and that Kaposi's sarcoma-associated herpesvirus (KSHV) lytic infection reduces PB formation through several specific interactions with viral RNA-binding protein ORF57.
|
31400113 |
2019 |