DisGeNET - a database of gene-disease associations

TNRC6A, trinucleotide repeat containing adaptor 6A, 27327

N. diseases: 39; N. variants: 27

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs8045064

Entrez Id:	27327;400511
Gene Symbol:	TNRC6A;LINC01567

TNRC6A;LINC01567

CUI:	C0002395
Disease:

Alzheimer's Disease

0.800

GeneticVariation

GWASDB

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.

23535033

2014

dbSNP:

rs8045064

Entrez Id:	27327;400511
Gene Symbol:	TNRC6A;LINC01567

TNRC6A;LINC01567

CUI:	C0002395
Disease:

Alzheimer's Disease

0.800

GeneticVariation

GWASCAT

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.

23535033

2014

dbSNP:

rs112927956

Entrez Id:	27327
Gene Symbol:	TNRC6A

TNRC6A

CUI:	C1314691
Disease:

Age at menarche

0.700

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019

dbSNP:

rs12708665

Entrez Id:	27327
Gene Symbol:	TNRC6A

TNRC6A

CUI:	C0005890
Disease:

Body Height

0.700

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019

dbSNP:

rs200528

Entrez Id:	27327
Gene Symbol:	TNRC6A

TNRC6A

CUI:	C0005823
Disease:

Blood Pressure

0.700

GeneticVariation

GWASCAT

Genetic overlap of chronic obstructive pulmonary disease and cardiovascular disease-related traits: a large-scale genome-wide cross-trait analysis.

30940143

2019

dbSNP:

rs200528

Entrez Id:	27327
Gene Symbol:	TNRC6A

TNRC6A

CUI:	C0024117
Disease:

Chronic Obstructive Airway Disease

0.700

GeneticVariation

GWASCAT

Genetic overlap of chronic obstructive pulmonary disease and cardiovascular disease-related traits: a large-scale genome-wide cross-trait analysis.

30940143

2019

dbSNP:

rs2188717

Entrez Id:	27327
Gene Symbol:	TNRC6A

TNRC6A

CUI:	C0871470
Disease:

Systolic Pressure

0.700

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019

dbSNP:

rs2188717

Entrez Id:	27327
Gene Symbol:	TNRC6A

TNRC6A

CUI:	C0871470
Disease:

Systolic Pressure

0.700

GeneticVariation

GWASCAT

Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.

30578418

2019

dbSNP:

rs34172651

Entrez Id:	27327
Gene Symbol:	TNRC6A

TNRC6A

CUI:	C0021704
Disease:

Intelligence

0.700

GeneticVariation

GWASCAT

A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.

29326435

2019

dbSNP:

rs7186893

Entrez Id:	27327
Gene Symbol:	TNRC6A

TNRC6A

CUI:	C1305855
Disease:

Body mass index

0.700

GeneticVariation

GWASCAT

Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.

30239722

2019

dbSNP:

rs7186893

Entrez Id:	27327
Gene Symbol:	TNRC6A

TNRC6A

CUI:	C0205682
Disease:

Waist-Hip Ratio

0.700

GeneticVariation

GWASCAT

Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.

30239722

2019

dbSNP:

rs7188873

Entrez Id:	27327
Gene Symbol:	TNRC6A

TNRC6A

CUI:	C0021704
Disease:

Intelligence

0.700

GeneticVariation

GWASCAT

A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.

29326435

2019

dbSNP:

rs7204281

Entrez Id:	27327
Gene Symbol:	TNRC6A

TNRC6A

CUI:	C1305855
Disease:

Body mass index

0.700

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019

dbSNP:

rs28512462

Entrez Id:	27327
Gene Symbol:	TNRC6A

TNRC6A

CUI:	C0596887
Disease:

mathematical ability

0.700

GeneticVariation

GWASCAT

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.

30038396

2018

dbSNP:

rs34172651

Entrez Id:	27327
Gene Symbol:	TNRC6A

TNRC6A

CUI:	C0021704
Disease:

Intelligence

0.700

GeneticVariation

GWASCAT

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.

29942086

2018

dbSNP:

rs34172651

Entrez Id:	27327
Gene Symbol:	TNRC6A

TNRC6A

CUI:	C0021704
Disease:

Intelligence

0.700

GeneticVariation

GWASCAT

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

29844566

2018

dbSNP:

rs7188873

Entrez Id:	27327
Gene Symbol:	TNRC6A

TNRC6A

CUI:	C0021704
Disease:

Intelligence

0.700

GeneticVariation

GWASCAT

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.

29942086

2018

dbSNP:

rs72768642

Entrez Id:	27327
Gene Symbol:	TNRC6A

TNRC6A

CUI:	C0021704
Disease:

Intelligence

0.700

GeneticVariation

GWASCAT

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.

29942086

2018

dbSNP:

rs77989568

Entrez Id:	27327
Gene Symbol:	TNRC6A

TNRC6A

CUI:	C0596887
Disease:

mathematical ability

0.700

GeneticVariation

GWASCAT

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.

30038396

2018

dbSNP:

rs11639856

Entrez Id:	27327
Gene Symbol:	TNRC6A

TNRC6A

CUI:	C0023467
Disease:

Leukemia, Myelocytic, Acute

0.700

GeneticVariation

GWASCAT

Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.

27903959

2017

dbSNP:

rs12596320

Entrez Id:	27327
Gene Symbol:	TNRC6A

TNRC6A

CUI:	C0023467
Disease:

Leukemia, Myelocytic, Acute

0.700

GeneticVariation

GWASCAT

Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.

27903959

2017

dbSNP:

rs12599552

Entrez Id:	27327
Gene Symbol:	TNRC6A

TNRC6A

CUI:	C0023467
Disease:

Leukemia, Myelocytic, Acute

0.700

GeneticVariation

GWASCAT

Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.

27903959

2017

dbSNP:

rs13336754

Entrez Id:	27327
Gene Symbol:	TNRC6A

TNRC6A

CUI:	C0023467
Disease:

Leukemia, Myelocytic, Acute

0.700

GeneticVariation

GWASCAT

Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.

27903959

2017

dbSNP:

rs1465423

Entrez Id:	27327
Gene Symbol:	TNRC6A

TNRC6A

CUI:	C0023467
Disease:

Leukemia, Myelocytic, Acute

0.700

GeneticVariation

GWASCAT

Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.

27903959

2017

dbSNP:

rs17177078

Entrez Id:	27327
Gene Symbol:	TNRC6A

TNRC6A

CUI:	C0023467
Disease:

Leukemia, Myelocytic, Acute

0.700

GeneticVariation

GWASCAT

Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.

27903959

2017