GLO1, glyoxalase I, 2739

N. diseases: 137; N. variants: 7
Disease: Mental Depression ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.330 Biomarker disease BEFREE These findings provide the basis for GLO1 inhibitors to treat depression and related psychiatric illnesses. 30628789 2019
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.330 Biomarker disease BEFREE Our findings indicate that GLO1 inhibitors may provide a novel and fast-acting pharmacotherapy for depression. 28322281 2018
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.330 Biomarker disease PSYGENET Quantitative real-time polymerase chain reaction experiments revealed that reduced expression of Glo1 mRNA was observed in major depressive and bipolar disorder patients in a current depressive state, as compared with healthy control subjects. 18455873 2008
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.330 AlteredExpression disease BEFREE Quantitative real-time polymerase chain reaction experiments revealed that reduced expression of Glo1 mRNA was observed in major depressive and bipolar disorder patients in a current depressive state, as compared with healthy control subjects. 18455873 2008
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.330 Biomarker disease PSYGENET Additional studies will examine whether glyoxalase-I has an impact beyond that of a biomarker to predict the genetic predisposition to anxiety- and depression-like behavior. 15858064 2005