GPR22, G protein-coupled receptor 22, 2845

N. diseases: 1; N. variants: 0
Disease: Degenerative polyarthritis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.030 GeneticVariation disease BEFREE An osteoarthritis (OA) susceptibility locus has been mapped to chromosome 7q22, to a region of high-linkage disequilibrium encompassing six genes: PRKAR2B, HBP1, COG5, GPR22, DUS4L and BCAP29. 22586168 2012
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.030 Biomarker disease BEFREE GWAS have reported structural genes (COL6A4), inflammation-related genes (PTGS2/PLA2G4A) and a locus on chr 7q22 (GPR22 and four other genes in the same linkage disequilibrium block) associated with osteoarthritis. 20090528 2010
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.030 Biomarker disease BEFREE GPR22-positive chondrocyte-like cells were also found in osteophytes in instability-induced OA. 20112360 2010