EPHA6, EPH receptor A6, 285220

N. diseases: 23; N. variants: 9
Disease: Neuropathy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0442874
Disease: Neuropathy
Neuropathy 		0.010 GeneticVariation group BEFREE Combining the series gave an estimated 2.5-fold higher risk of neuropathy (95% CI, 1.46-4.31; <i>P</i> = 9.1 × 10<sup>-4</sup>).<b>Conclusions:</b> This first study sequencing <i>EPHA</i> genes revealed that low-frequency variants in <i>EPHA6, EPHA5</i>, and <i>EPHA8</i> contribute to the susceptibility to paclitaxel-induced neuropathy. 27582484 2017