TRAV4, T cell receptor alpha variable 4, 28689

N. diseases: 3; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.010 Biomarker group BEFREE Here we show that the structures of two distinct TCRs (TRAV4<sup>+</sup>TRAJ21<sup>+</sup>-TRBV28<sup>+</sup>TRBJ2-3<sup>+</sup> and TRAV4 <sup>+</sup> TRAJ8<sup>+</sup>-TRBV9<sup>+</sup>TRBJ2-1<sup>+</sup>), originating from a polyclonal T-cell repertoire, bind to HLA-B*07:02, presenting a 13-amino-acid-long tumour-associated peptide, NY-ESO-1<sub>60-72</sub>. 29531227 2018
CUI: C0011334
Disease: Dental caries
Dental caries 		0.010 GeneticVariation disease BEFREE Finally, we observed higher expression in children and teenagers with low caries experience, correlating with specific alleles in TRAV4. 23657505 2013
CUI: C0333519
Disease: Caries (morphologic abnormality)
Caries (morphologic abnormality) 		0.010 GeneticVariation disease BEFREE Finally, we observed higher expression in children and teenagers with low caries experience, correlating with specific alleles in TRAV4. 23657505 2013