GPX1, glutathione peroxidase 1, 2876

N. diseases: 290; N. variants: 12
Disease: Progression of prostate cancer ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1739135
Disease: Progression of prostate cancer
Progression of prostate cancer 		0.020 GeneticVariation disease BEFREE For the analysis of GPx1 polymorphism and progression of prostate cancer, no significant association were found in the dominant model (fixed effects OR 1.20, 95 % CI 0.95-1.52), recessive model (fixed effects OR 0.69, 95 % CI 0.48-1.00) and co-dominant genetic model (fixed effects OR 0.95, 95 % CI 0.79-1.15). 22699881 2012
CUI: C1739135
Disease: Progression of prostate cancer
Progression of prostate cancer 		0.020 GeneticVariation disease BEFREE The present data provide evidence that GPx1 Pro198Leu polymorphism may be associated with the development and progression of PCa and older ages may influence the association.between GPx1 Pro198Leu polymorphism and PCa. 21993316 2011