GPX3, glutathione peroxidase 3, 2878

N. diseases: 156; N. variants: 6
Disease: Adenocarcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.340 GeneticVariation group BEFREE PF-based chemotherapy significantly decreased risk of death for patients carrying GPx3 rs736775 TC/CC and age ≤ 60 years or with diffused type adenocarcinoma compared to surgery alone. 30114685 2018
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.340 GeneticVariation group BEFREE To verify the methylation status of THBS1, GPX3, and COX2 genes and to evaluate their association with Helicobacter pylori in gastric adenocarcinomas. 24014049 2014
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.340 Biomarker group BEFREE Positive ALDH1A3 and negative GPX3 expressions were significantly associated with lymph node metastasis and invasion of SC/ASCs and ACs. 24167362 2013
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.340 Biomarker group CTD_human Varied pathways of stage IA lung adenocarcinomas discovered by integrated gene expression analysis. 21552421 2011
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.340 Biomarker group BEFREE However, weak to absent GPx3 staining was observed in Barrett's dysplasia and adenocarcinoma samples where the promoter was hypermethylated. 16229808 2005
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.340 AlteredExpression group LHGDN However, weak to absent GPx3 staining was observed in Barrett's dysplasia and adenocarcinoma samples where the promoter was hypermethylated. 16229808 2005