REM Sleep Behavior Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
This case showed typical RBD symptoms with REM sleep without atonia on polysomnography.
|
31777313 |
2020 |
REM Sleep Behavior Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
Future studies should include control group for the evaluation of REM sleep without atonia as marker for neurodegeneration also in non-clinical population and target RBD as precursor of neurodegeneration to develop protective trials.
|
30503716 |
2019 |
REM Sleep Behavior Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
REM sleep behaviour disorder (RBD) is characterised by violent behaviours (screaming, kicking, vivid dreams) during REM sleep.
|
28215911 |
2019 |
REM Sleep Behavior Disorder
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We visually quantified phasic, "any," and tonic RSWA in the submentalis (SM) and anterior tibialis (AT) muscles, and the automated Ferri REM Atonia Index during polysomnography in adults without RBD aged 21-88.
|
31587043 |
2019 |
REM Sleep Behavior Disorder
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
REM sleep muscle activity in idiopathic REM sleep behavior disorder predicts phenoconversion.
|
31420463 |
2019 |
REM Sleep Behavior Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
In REM sleep, both had motor behaviors and increased phasic/tonic muscle activities confirming RBD.
|
31392847 |
2019 |
REM Sleep Behavior Disorder
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Non-parametric correlations were also computed in patients with iRBD between FEOBV uptake and muscle tonic and phasic activity during REM sleep.
|
31078078 |
2019 |
REM Sleep Behavior Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
The percentages of movements and the median inter-movement distance during REM and non-REM (NREM) sleep were used for distinguishing C, RBD and PLMD by combining three optimized classifiers in a 5-fold cross-validation scheme.
|
30468824 |
2019 |
REM Sleep Behavior Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
REM Sleep without atonia correlates with abnormal vestibular-evoked myogenic potentials in isolated REM sleep behavior disorder.
|
31310647 |
2019 |
REM Sleep Behavior Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
REM sleep behavior disorder (RBD) is a parasomnia wherein a loss of REM sleep atonia manifests as dream-enactment, often violent.
|
29102236 |
2018 |
REM Sleep Behavior Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
This review addresses the neuronal substrates of REM sleep generation and modulation and how its impairment may lead to REM sleep behavior disorder.
|
29846796 |
2018 |
REM Sleep Behavior Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
Patients with iRBD were older, had an older RBD onset age and higher REM sleep phasic and tonic muscular activities than NT1-RBD.
|
29740055 |
2018 |
REM Sleep Behavior Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
We found that Parkinson's disease patients with RBD showed decreased locus coeruleus neuromelanin signal on MRI (P < 0.001) and widespread reduced binding of 11C-MeNER (P < 0.001), which correlated with amount of REM sleep without atonia.
|
29272343 |
2018 |
REM Sleep Behavior Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
To evaluate REM sleep without atonia (RSWA) in REM sleep behavior disorder (RBD) several automatic algorithms have been developed.
|
29773203 |
2018 |
REM Sleep Behavior Disorder
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Ventromedial medulla inhibitory neuron inactivation induces REM sleep without atonia and REM sleep behavior disorder.
|
29402935 |
2018 |
REM Sleep Behavior Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
Dream enacting behavior (DEB) during REM sleep is a characteristic feature of REM sleep behavior disorder (RBD), the most specific prodromal symptom for Parkinson's disease (PD) and related synucleinopathies.
|
30007509 |
2018 |
REM Sleep Behavior Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
REM sleep without atonia with REM sleep-related motor events: broadening the spectrum of REM sleep behavior disorder.
|
30239958 |
2018 |
REM Sleep Behavior Disorder
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Study subjects included 19 patients with late-onset psychiatric disorders who exhibited REM sleep without atonia (RWA), which is a hallmark of RBD on polysomnography, at our psychiatric ward.
|
29536584 |
2018 |
REM Sleep Behavior Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
In the late 50s Michel Jouvet discovered the presence of muscle atonia during REM sleep in cats and created the first model of REM sleep behavior disorder.
|
30017825 |
2018 |
REM Sleep Behavior Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
RBD patients seem to have a milder OSA phenotype (possible reflecting a protective role conferred by the maintenance of muscle tone during REM sleep) and to be less prone to obesity and snoring than non-RBD patients.
|
28673760 |
2017 |
REM Sleep Behavior Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
We presume that in patients with RBD and OSAS both pathologies contribute in varying degrees to the emergence of RBD symptoms by a destabilization of REM sleep.
|
28545360 |
2017 |
REM Sleep Behavior Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
To assess sleep characteristics and the occurrence of abnormal muscle activity during sleep, such as REM sleep without atonia (RSWA), REM sleep behavior disorder (RBD), and periodic leg movements during sleep (PLMS), in patients with amyotrophic lateral sclerosis (ALS).
|
27027974 |
2017 |
REM Sleep Behavior Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
Complex behaviours occurring during REM sleep were further classified as 'classically-defined' and 'pantomime-like' REM sleep behaviour disorder episodes, based on their duration and on their pattern (i.e. brief and vivid-energetic in the first case, longer and with subcontinuous gesturing mimicking daily life activity in the second case).
|
28472332 |
2017 |
REM Sleep Behavior Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
High doses are especially efficacious in REM sleep, suggesting that SO could be used to treat REM sleep behavior disorder.
|
28619175 |
2017 |
REM Sleep Behavior Disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
Patients were categorized as clinical RBD (DEB and IRWA), sub-DEB positive (DEB only), subclinical RBD (IRWA only), or normal REM sleep.
|
28923293 |
2017 |