PYCARD, PYD and CARD domain containing, 29108

N. diseases: 294; N. variants: 2
Disease: Cervical Intraepithelial Neoplasia Grade 2/3 ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2986622
Disease: Cervical Intraepithelial Neoplasia Grade 2/3
Cervical Intraepithelial Neoplasia Grade 2/3 		0.020 Biomarker disease BEFREE Sensitivity and specificity estimates of DNA and mRNA testing to detect cervical intraepithelial neoplasia grade 2, 3, or invasive cancer were obtained from 2 published trials: the US Clinical Evaluation of APTIMA mRNA (CLEAR) study for ASC-US triage and the French APTIMA Screening Evaluation (FASE) study for cotesting. 26225945 2015
CUI: C2986622
Disease: Cervical Intraepithelial Neoplasia Grade 2/3
Cervical Intraepithelial Neoplasia Grade 2/3 		0.020 Biomarker disease BEFREE In women with ASC-US, HPV genotyping for the eight oncogenic types showed higher specificity (81 vs 46%) and positive predictive value (PPV, 44 vs 26%) in predicting CIN 2/3/carcinoma compared to HPV DNA testing. 18500260 2008