TBK1, TANK binding kinase 1, 29110

N. diseases: 207; N. variants: 26
Disease: ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED (HERPES-SPECIFIC), SUSCEPTIBILITY TO, 8 ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4693542
Disease: ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED (HERPES-SPECIFIC), SUSCEPTIBILITY TO, 8
ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED (HERPES-SPECIFIC), SUSCEPTIBILITY TO, 8 		0.600 Biomarker phenotype GENOMICS_ENGLAND Mutations in the TLR3 signaling pathway and beyond in adult patients with herpes simplex encephalitis. 26513235 2015
CUI: C4693542
Disease: ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED (HERPES-SPECIFIC), SUSCEPTIBILITY TO, 8
ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED (HERPES-SPECIFIC), SUSCEPTIBILITY TO, 8 		0.600 GeneticVariation phenotype UNIPROT Mutations in the TLR3 signaling pathway and beyond in adult patients with herpes simplex encephalitis. 26513235 2015
CUI: C4693542
Disease: ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED (HERPES-SPECIFIC), SUSCEPTIBILITY TO, 8
ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED (HERPES-SPECIFIC), SUSCEPTIBILITY TO, 8 		0.600 GeneticVariation phenotype UNIPROT Heterozygous TBK1 mutations impair TLR3 immunity and underlie herpes simplex encephalitis of childhood. 22851595 2012
CUI: C4693542
Disease: ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED (HERPES-SPECIFIC), SUSCEPTIBILITY TO, 8
ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED (HERPES-SPECIFIC), SUSCEPTIBILITY TO, 8 		0.600 SusceptibilityMutation phenotype CLINVAR