GRM2, glutamate metabotropic receptor 2, 2912

N. diseases: 104; N. variants: 1
Disease: Panic Disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030319
Disease: Panic Disorder
Panic Disorder 		0.020 Biomarker disease BEFREE These data demonstrate that a panic-prone state leads to specific reduction in mGluR2 function within the amygdala network and facilitates fear, and mGluR2 PAMs could be a targeted treatment for panic symptoms in PD and PTSD patients. 30108314 2020
CUI: C0030319
Disease: Panic Disorder
Panic Disorder 		0.020 Biomarker disease BEFREE This article will cover the importance of immediate and proper treatment, the gap in the current management of PD with special emphasis on pharmacotherapy, and evidence regarding the novel anti-panic drugs including the drugs in developments such as metabotropic glutamate (mGlu 2/3) agonist and levetiracetam. 30905115 2019