GRM8, glutamate metabotropic receptor 8, 2918

N. diseases: 56; N. variants: 13
Disease: Schizophrenia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.360 GeneticVariation disease BEFREE Our findings indicate that rs712723 in GRM8 may play an important role in the pathogenesis of SCZ. 30288643 2018
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.360 Biomarker disease BEFREE We demonstrated the genetic association of GRM7 and GRM8 with SCZ and MDD in the Han Chinese population. 26655190 2016
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.360 Biomarker disease BEFREE This study indicates that the GRM8 gene may play an important role in the pathogenesis of schizophrenia. 25588301 2014
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.360 Biomarker disease PSYGENET These data provide a potential role for mGluR8 in anxiety and suggest that mGluR8 may not be a therapeutic target for schizophrenia. 17434465 2007
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.360 Biomarker disease BEFREE These data provide a potential role for mGluR8 in anxiety and suggest that mGluR8 may not be a therapeutic target for schizophrenia. 17434465 2007
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.360 Biomarker disease PSYGENET Thus, we conclude that at least one susceptibility locus for schizophrenia is located within the GRM8 region in Japanese. 15211621 2004
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.360 GeneticVariation disease BEFREE Thus, we conclude that at least one susceptibility locus for schizophrenia is located within the GRM8 region in Japanese. 15211621 2004
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.360 GeneticVariation disease BEFREE Both variants, present at high frequencies, failed to demonstrate any significant association with schizophrenia (mGluR7 [Tyr433Phe] allele: P=0.33; genotype: P=0.63; mGluR8 [2846-C/T] allele: P=0.72; genotype: P=0.63). 11163549 2001
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.360 Biomarker disease PSYGENET Both variants, present at high frequencies, failed to demonstrate any significant association with schizophrenia (mGluR7 [Tyr433Phe] allele: P=0.33; genotype: P=0.63; mGluR8 [2846-C/T] allele: P=0.72; genotype: P=0.63). 11163549 2001