CXCL2, C-X-C motif chemokine ligand 2, 2920

N. diseases: 186; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0243026
Disease: Sepsis
Sepsis
0.040 Biomarker disease BEFREE IL-13 attenuates early local CXCL2-dependent neutrophil recruitment for Candida albicans clearance during a severe murine systemic infection. 30514570 2019
CUI: C0243026
Disease: Sepsis
Sepsis
0.040 AlteredExpression disease BEFREE Tephrosin attenuates sepsis induced acute lung injury in rats by impeding expression of ICAM-1 and MIP-2. 29432911 2018
CUI: C0243026
Disease: Sepsis
Sepsis
0.040 Biomarker disease BEFREE Several studies have implicated the CXCL2 chemokine as a mediator in the development of sepsis. 17944017 2007
CUI: C0243026
Disease: Sepsis
Sepsis
0.040 GeneticVariation disease BEFREE We hypothesized that CXCL2 polymorphisms may confer susceptibility to sepsis and performed an association study using 178 severe sepsis patients and 357 population-based controls. 16421598 2006
CUI: C0243026
Disease: Sepsis
Sepsis
0.040 GeneticVariation disease LHGDN A CXCL2 tandem repeat promoter polymorphism is associated with susceptibility to severe sepsis in the Spanish population. 16421598 2006