GTF3A, general transcription factor IIIA, 2971

N. diseases: 21; N. variants: 3
Disease: Decreased adipose tissue ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4022459
Disease: Decreased adipose tissue
Decreased adipose tissue 		0.010 AlteredExpression phenotype BEFREE Here, we demonstrate a functionally significant genetic variation at the aP2 locus in humans that results in decreased adipose tissue aP2 expression due to alteration of the CAAT box/enhancer-binding protein binding and reduced transcriptional activity of the aP2 promoter. 16641093 2006