SEC61A1, SEC61 translocon subunit alpha 1, 29927

N. diseases: 30; N. variants: 3
Disease: Immunosuppression ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4048329
Disease: Immunosuppression
Immunosuppression 		0.010 Biomarker disease BEFREE The skin lesions and immunosuppression that are characteristic of this disease result from the action of mycolactone, which targets the Sec61 complex and inhibits the co-translational translocation of secretory proteins into the endoplasmic reticulum. 28219954 2017