IL19, interleukin 19, 29949

N. diseases: 103; N. variants: 40
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases
0.310 AlteredExpression group BEFREE We also demonstrate a large increase in levels of IL-19 in urine of patients with chronic kidney disease, which significantly correlated with estimated glomerular filtration rate levels. 24714768 2015
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases
0.310 Biomarker group CTD_human Interleukin-19 as a translational indicator of renal injury. 24714768 2015
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.310 Biomarker disease PSYGENET These results suggest that the IL-19 gene might slightly contribute to the genetic risk of schizophrenia. 24361379 2014
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.310 GeneticVariation disease BEFREE These results suggest that the IL-19 gene might slightly contribute to the genetic risk of schizophrenia. 24361379 2014
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.310 GeneticVariation disease BEFREE There were no significant differences in genotype frequencies of IL-10*T/T, IL-10*T/C, and IL-10*C/C as well as allelic frequencies of IL-10*T and IL-10*C between patients with major depression and controls in the Korean population. 11952921 2002
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.310 GeneticVariation disease BEFREE There were no significant differences in genotype frequencies of IL-10*T/T, IL-10*T/C, and IL-10*C/C as well as allelic frequencies of IL-10*T and IL-10*C between patients with major depression and controls in the Korean population. 11952921 2002
CUI: C0403447
Disease: Chronic Kidney Insufficiency
Chronic Kidney Insufficiency
0.300 Biomarker disease CTD_human Interleukin-19 as a translational indicator of renal injury. 24714768 2015
Diabetes Mellitus, Insulin-Dependent
0.300 Biomarker disease CTD_human Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. 19430480 2009
CUI: C0205734
Disease: Diabetes, Autoimmune
Diabetes, Autoimmune
0.300 Biomarker disease CTD_human Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. 19430480 2009
CUI: C0342302
Disease: Brittle diabetes
Brittle diabetes
0.300 Biomarker disease CTD_human Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. 19430480 2009
CUI: C3837958
Disease: Diabetes Mellitus, Ketosis-Prone
Diabetes Mellitus, Ketosis-Prone
0.300 Biomarker disease CTD_human Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. 19430480 2009
CUI: C4554117
Disease: Diabetes Mellitus, Sudden-Onset
Diabetes Mellitus, Sudden-Onset
0.300 Biomarker disease CTD_human Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. 19430480 2009
CUI: C0023434
Disease: Chronic Lymphocytic Leukemia
Chronic Lymphocytic Leukemia
0.300 Biomarker disease CTD_human Scan of 977 nonsynonymous SNPs in CLL4 trial patients for the identification of genetic variants influencing prognosis. 18006695 2008
CUI: C0033860
Disease: Psoriasis
Psoriasis
0.200 AlteredExpression disease BEFREE Therefore, measurement of serum IL-19 provides clinicians with an objective disease-activity assessment tool for psoriasis and atopic dermatitis patients. 30914699 2019
CUI: C0033860
Disease: Psoriasis
Psoriasis
0.200 Biomarker disease BEFREE Here we show that a deficiency of the TNF superfamily molecule TWEAK (TNFSF12) in mice results in defective maintenance of AD-specific T helper type 2 (Th2) and psoriasis-specific Th17 cells in the skin, and impaired expression of disease-characteristic chemokines and cytokines, such as CCL17 and TSLP in AD, and CCL20 and IL-19 in psoriasis. 28530223 2017
CUI: C0033860
Disease: Psoriasis
Psoriasis
0.200 GeneticVariation disease BEFREE Interleukin (IL)-10 family cytokines IL-10, IL-19, IL-20 and IL-24 have been implicated in autoimmune diseases and we have previously reported that genetic variants in the IL10 gene cluster were associated with psoriasis. 28150860 2017
CUI: C0033860
Disease: Psoriasis
Psoriasis
0.200 AlteredExpression disease BEFREE Interleukin-19 (IL-19), a pro-inflammatory cytokine known to stimulate the production of T helper type 2 (Th2) cytokines, is induced by IL-17A and highly expressed in the lesional skin of psoriasis and atopic dermatitis (AD). 28597022 2017
CUI: C0033860
Disease: Psoriasis
Psoriasis
0.200 GeneticVariation disease GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
CUI: C0033860
Disease: Psoriasis
Psoriasis
0.200 AlteredExpression disease BEFREE Resveratrol ameliorates psoriasis, and changes expression of retinoic acid stimulated genes, IL-17 signalling pathways, IL-17A and IL-19 mRNA levels in a beneficial manner, which suggests resveratrol, might have a role in the treatment of psoriasis and should be explored further in a human setting. 25965695 2015
CUI: C0033860
Disease: Psoriasis
Psoriasis
0.200 Biomarker disease BEFREE Interleukin 19 (IL-19), IL-20 and IL-24 signal through type I and type II IL-20 receptors and are associated with inflammatory skin diseases such as psoriasis and atopic dermatitis. 23793061 2013
CUI: C0033860
Disease: Psoriasis
Psoriasis
0.200 AlteredExpression disease BEFREE It is known that expression of IL-19 is increased in the epidermis of patients with psoriasis, which is a Th1 dominant disease. 22103848 2011
CUI: C0031090
Disease: Periodontal Diseases
Periodontal Diseases
0.200 Biomarker group RGD Adaptive immune response in osteoclastic bone resorption induced by orally administered Aggregatibacter actinomycetemcomitans in a rat model of periodontal disease. 20618701 2010
CUI: C0033860
Disease: Psoriasis
Psoriasis
0.200 AlteredExpression disease BEFREE IL-17A and IL-19 are highly expressed in chronic inflammatory diseases, such as psoriasis and asthma. 18539194 2008
CUI: C0033860
Disease: Psoriasis
Psoriasis
0.200 AlteredExpression disease BEFREE IL-23 induced IL-19 and IL-24 expression in mouse skin, and both genes were also elevated in human psoriasis. 17074928 2006
CUI: C0033860
Disease: Psoriasis
Psoriasis
0.200 AlteredExpression disease BEFREE During treatment with calcipotriol or CsA, IL-19 and IL-20 mRNA levels decrease in accordance with the clinical improvement of psoriasis. 16225599 2005