GZMB, granzyme B, 3002

N. diseases: 290; N. variants: 5
Disease: leukemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023418
Disease: leukemia
leukemia 		0.030 AlteredExpression disease BEFREE We found NKL-IL15 cells displayed a significant high cytolysis activity against both human leukemia cell lines and primary leukemia cells from patients, accompanied with up-regulated expression of molecules related to NK cell cytotoxicity such as perforin, granzyme B and NKp80. 29737430 2018
CUI: C0023418
Disease: leukemia
leukemia 		0.030 Biomarker disease BEFREE The quantity of granzyme B inhibitor PI-9 in the leukemia blasts was greater in patients who were MRD positive (P = 0.038). 25281696 2014
CUI: C0023418
Disease: leukemia
leukemia 		0.030 Biomarker disease LHGDN Herein, we show that granzyme B initiates caspase processing but cannot fully process procaspase-3 in intact Jurkat T leukemia or NT2 neuronal cells. 12648450 2003