GZMB, granzyme B, 3002

N. diseases: 290; N. variants: 5
Disease: Breast Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.340 Biomarker disease BEFREE Synergistic effect of granzyme B-azurin fusion protein on breast cancer cells. 30937652 2019
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.340 AlteredExpression disease BEFREE Granzyme B production by activated B cells derived from breast cancer-draining lymph nodes. 31357083 2019
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.340 AlteredExpression disease BEFREE Inhibition of the actin response by knocking down CDC42 or N-WASP led to a significant increase in granzyme B levels in target cells and was sufficient to convert resistant breast cancer cell lines into a highly susceptible phenotype. 30104240 2018
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.340 GeneticVariation disease BEFREE Our data suggest that reduction in the proportion of gammadelta T cells and granzyme B gene polymorphism leads to defective immune function in breast cancer patients. 19446661 2009
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.340 Biomarker disease CTD_human Our data suggest that reduction in the proportion of gammadelta T cells and granzyme B gene polymorphism leads to defective immune function in breast cancer patients. 19446661 2009