GZMB, granzyme B, 3002

N. diseases: 290; N. variants: 5
Disease: Childhood Lymphoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1332979
Disease: Childhood Lymphoma
Childhood Lymphoma 		0.030 AlteredExpression disease BEFREE This suggests that GzB expression may be a factor contributing to the favourable response of this lymphoma to treatment. 25168906 2014
CUI: C1332979
Disease: Childhood Lymphoma
Childhood Lymphoma 		0.030 AlteredExpression disease BEFREE Moreover, these findings demonstrate the expression of GzB and Perforin in this lymphoma is not solely due its presumed CTL origin, but that oncogenic signalling is actively influencing the expression of these proteins. 21326808 2011
CUI: C1332979
Disease: Childhood Lymphoma
Childhood Lymphoma 		0.030 Biomarker disease BEFREE The expression of proteinase inhibitor 9 (PI-9), a molecule that inactivates granzyme B, is considered an immune escape mechanism in lymphoma. 16373664 2006