H1-2, H1.2 linker histone, cluster member, 3006

N. diseases: 21; N. variants: 4
Disease: Diabetic Retinopathy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy 		0.010 AlteredExpression disease BEFREE Importantly, AAV-mediated histone HIST1H1C overexpression in the retinas leads to increased autophagy, inflammation, glial activation and neuron loss, similar to the pathological changes identified in the early stage of diabetic retinopathy. 28409999 2017