HARS1, histidyl-tRNA synthetase 1, 3035

N. diseases: 127; N. variants: 16
Disease: Polymyositis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0085655
Disease: Polymyositis
Polymyositis 		0.020 Biomarker disease BEFREE Although the HLA DRB1*03:01 allele showed slightly stronger associations with adult and juvenile dermatomyositis, and HLA B*08:01 with polymyositis and anti-Jo-1 autoantibody-positive myositis, multiple alleles of AH8.1 were required for the full risk effects. 26291516 2015
CUI: C0085655
Disease: Polymyositis
Polymyositis 		0.020 Biomarker disease LHGDN Critical requirement for professional APCs in eliciting T cell responses to novel fragments of histidyl-tRNA synthetase (Jo-1) in Jo-1 antibody-positive polymyositis. 12471150 2002