HCRTR2, hypocretin receptor 2, 3062

N. diseases: 37; N. variants: 11
Disease: Depressive disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.030 Biomarker disease BEFREE Moreover, 5-HT1AR and OX2R are involved in the pathogenesis of neurological diseases such as depression with deficiency of hippocampus plasticity. 30481562 2019
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.030 Biomarker disease BEFREE The results of the present study suggest that the C‑terminus of OX2R is important for its role in various physiological and pathological processes, and may therefore be associated with such disorders as depression and anorexia. 28487995 2017
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.030 Biomarker disease BEFREE Lack of Association between Genetic Polymorphism of Circadian Genes (PER2, PER3, CLOCK and OX2R) with Late Onset Depression and Alzheimer's Disease in a Sample of a Brazilian Population (Circadian Genes, Late-Onset Depression and Alzheimer's Disease). 27335043 2016