HCRTR2, hypocretin receptor 2, 3062

N. diseases: 37; N. variants: 11
Disease: Depressed mood ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0344315
Disease: Depressed mood
Depressed mood 		0.030 Biomarker phenotype BEFREE Moreover, 5-HT1AR and OX2R are involved in the pathogenesis of neurological diseases such as depression with deficiency of hippocampus plasticity. 30481562 2019
CUI: C0344315
Disease: Depressed mood
Depressed mood 		0.030 Biomarker phenotype BEFREE The results of the present study suggest that the C‑terminus of OX2R is important for its role in various physiological and pathological processes, and may therefore be associated with such disorders as depression and anorexia. 28487995 2017
CUI: C0344315
Disease: Depressed mood
Depressed mood 		0.030 Biomarker phenotype BEFREE Lack of Association between Genetic Polymorphism of Circadian Genes (PER2, PER3, CLOCK and OX2R) with Late Onset Depression and Alzheimer's Disease in a Sample of a Brazilian Population (Circadian Genes, Late-Onset Depression and Alzheimer's Disease). 27335043 2016