HCRTR2, hypocretin receptor 2, 3062

N. diseases: 37; N. variants: 11
Disease: Sleep Disorders ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0851578
Disease: Sleep Disorders
Sleep Disorders 		0.020 Biomarker group BEFREE Expression of the hypocretin/orexin receptor HCRTR2, which has been implicated in narcolepsy, correlated with sleep disturbance. 16376318 2006
CUI: C0851578
Disease: Sleep Disorders
Sleep Disorders 		0.020 GeneticVariation group BEFREE This evidence suggests that the structure of the OX2R gene, and its homologue, the OX1R gene, both members of the G protein-coupled receptor (GPCR) family, and the gene encoding the peptide ligands, the prepro-orexin/hypocretin gene, may be variables in the etiology of sleep disorders. 15274044 2004