HDAC1, histone deacetylase 1, 3065

N. diseases: 277; N. variants: 1
Disease: Conventional (Clear Cell) Renal Cell Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0279702
Disease: Conventional (Clear Cell) Renal Cell Carcinoma
Conventional (Clear Cell) Renal Cell Carcinoma 		0.040 Biomarker disease BEFREE A novel human lncRNA SANT1 <i>cis</i>-regulates the expression of <i>SLC47A2</i> by altering SFPQ/E2F1/HDAC1 binding to the promoter region in renal cell carcinoma. 30951404 2019
CUI: C0279702
Disease: Conventional (Clear Cell) Renal Cell Carcinoma
Conventional (Clear Cell) Renal Cell Carcinoma 		0.040 PosttranslationalModification disease BEFREE Elevated histone H3 acetylation and loss of the Sp1-HDAC1 complex de-repress the GM2-synthase gene in renal cell carcinoma. 30463940 2019
CUI: C0279702
Disease: Conventional (Clear Cell) Renal Cell Carcinoma
Conventional (Clear Cell) Renal Cell Carcinoma 		0.040 Biomarker disease BEFREE Collectively, these results demonstrate that simvastatin restores RhoA function through HDAC1 inhibition; therefore, simvastatin might serve as adjunct therapy for RCC induced by 3MC. 30872677 2019
CUI: C0279702
Disease: Conventional (Clear Cell) Renal Cell Carcinoma
Conventional (Clear Cell) Renal Cell Carcinoma 		0.040 PosttranslationalModification disease BEFREE HDAC1-induced epigenetic silencing of ASPP2 promotes cell motility, tumour growth and drug resistance in renal cell carcinoma. 29890207 2018