HDAC2, histone deacetylase 2, 3066

N. diseases: 257; N. variants: 3
Disease: Peyronie Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030848
Disease: Peyronie Disease
Peyronie Disease 		0.230 AlteredExpression disease BEFREE The mRNA expression of HDAC2, 3, 4, 5, 7, 8, 10, and 11 was higher in fibroblasts isolated from PD plaque than in fibroblasts isolated from normal TA tissue. 29706035 2018
CUI: C0030848
Disease: Peyronie Disease
Peyronie Disease 		0.230 Biomarker disease BEFREE Specific inhibition of HDAC2 with RNA interference may represent a novel targeted therapy for PD. 24841412 2014
CUI: C0030848
Disease: Peyronie Disease
Peyronie Disease 		0.230 Biomarker disease RGD Specific inhibition of HDAC2 with RNA interference may represent a novel targeted therapy for PD. 24841412 2014
CUI: C0030848
Disease: Peyronie Disease
Peyronie Disease 		0.230 Biomarker disease BEFREE Decoding the individual function of the HDAC isoforms by use of siRNA technology, preferably siRNA for HDAC2, may lead to the development of specific and safe epigenetic therapies for PD. 23770939 2013