HDAC2, histone deacetylase 2, 3066

N. diseases: 257; N. variants: 3
Disease: Osteosarcoma of bone ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone 		0.040 Biomarker disease BEFREE Histone deacetylase 2 is involved in DNA damage-mediated cell death of human osteosarcoma cells through stimulation of the ATM/p53 pathway. 30868056 2019
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone 		0.040 Biomarker disease BEFREE It suggested that targeted inhibition of HDAC2/NF-κB/IL-6 might be a potential approach for OS therapy. 30706385 2019
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone 		0.040 AlteredExpression disease BEFREE HDAC2 expression on human osteosarcoma tissues was evaluated. 30509303 2018
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone 		0.040 Biomarker disease BEFREE Suppression of HDAC2 in Spinal Cord Alleviates Mechanical Hyperalgesia and Restores KCC2 Expression in a Rat Model of Bone Cancer Pain. 29482000 2018