HFE, homeostatic iron regulator, 3077

N. diseases: 415; N. variants: 59
Disease: Acute myocardial infarction ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0155626
Disease: Acute myocardial infarction
Acute myocardial infarction 		0.030 GeneticVariation disease BEFREE The results of this large individual patient data meta-analysis do not support the view that HFE gene mutations are associated with an increased risk of coronary heart disease or acute myocardial infarction. 20031541 2008
CUI: C0155626
Disease: Acute myocardial infarction
Acute myocardial infarction 		0.030 GeneticVariation disease BEFREE We studied the relation between HFE mutations and acute myocardial infarction in two case-control studies involving two sets of subjects representing different age groups from different geographic regions in Italy. 12850485 2004
CUI: C0155626
Disease: Acute myocardial infarction
Acute myocardial infarction 		0.030 GeneticVariation disease BEFREE Conclusions-Male carriers of the common hemochromatosis gene mutation are at 2-fold risk for first acute myocardial infarction compared with noncarriers. 10491370 1999