HMGA1, high mobility group AT-hook 1, 3159

N. diseases: 206; N. variants: 5
Disease: Tumor Initiation ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0598935
Disease: Tumor Initiation
Tumor Initiation 		0.030 Biomarker phenotype BEFREE Interestingly, HMGA1 silencing also leads to reduced tumor initiation ability in vivo. 27486901 2016
CUI: C0598935
Disease: Tumor Initiation
Tumor Initiation 		0.030 Biomarker phenotype BEFREE Using positional cloning strategies, we and others previously identified HMGA1, HMGA2, RAD51L1, MORF, and, more recently, NCOA1 as primary target (fusion) genes associated with tumor initiation in four of these distinct cytogenetic subgroups. 22965931 2013
CUI: C0598935
Disease: Tumor Initiation
Tumor Initiation 		0.030 GeneticVariation phenotype BEFREE For the first two subgroups, aberrations of the HMGIC and HMGIY genes have been described and are held responsible for tumor initiation. 9973936 1999