HMMR, hyaluronan mediated motility receptor, 3161

N. diseases: 117; N. variants: 6
Disease: Multiple Myeloma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.060 AlteredExpression disease BEFREE The expression of RHAMM and other centrosome-associated genes are known to correlate with the extent of centrosome amplification in multiple myeloma, and with poor prognosis. 18297535 2008
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.060 AlteredExpression disease BEFREE As expression of RHAMM in MM contributes to genetic instability, we tested effects of RHAMM. 17213289 2007
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.060 Biomarker disease BEFREE Here, we investigate the relationship between RHAMM and centrosomal abnormalities within multiple myeloma patient samples. 15705883 2005
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.060 AlteredExpression disease BEFREE Absolute RHAMM expression and the RHAMM-exon4/RHAMMFL ratio are only partially correlated in MM PCs; in cell lines, absolute RHAMM expression is elevated in mitosis, while RHAMM ratios remain stable. 15105292 2004
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.060 Biomarker disease BEFREE RHAMM contributes to genetic instability in MM; therefore, we speculate that it may also contribute to genetic instability in WM. 12720129 2003
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.060 AlteredExpression disease BEFREE RT-PCR analysis of sorted blood or BM cells from 22 MM patients showed that overexpression of RHAMM variants is characteristic of MM B cells and BM plasma cells in all patients tested. 10029598 1999