HMOX1, heme oxygenase 1, 3162

N. diseases: 666; N. variants: 9
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.320 GeneticVariation disease BEFREE The number of HO-1 promoter GT(n) polymorphism is increased in both IDCM and CRF children with HF, but is unrelated to plasma markers of different pathological processes. 25822459 2015
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.320 GeneticVariation disease BEFREE HMOX1 rs743811 associated with chronic kidney disease stage (OR=3.0, P=0.0001) in the University of Illinois cohort and end-stage renal disease (OR=10.0, P=0.0003) in the Walk-Treatment of Pulmonary Hypertension and Sickle cell Disease with Sildenafil Therapy cohort. 26206798 2015
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.320 Therapeutic disease CTD_human Nicorandil, a K(atp) channel opener, alleviates chronic renal injury by targeting podocytes and macrophages. 22622455 2012