HNF4A, hepatocyte nuclear factor 4 alpha, 3172

N. diseases: 340; N. variants: 74
Disease: Metabolic Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025517
Disease: Metabolic Diseases
Metabolic Diseases 		0.040 Biomarker group BEFREE Previous studies have shown that the melanocortin 4 receptor (MC4R) and hepatocyte nuclear factor 4 alpha (HNF4α) genes are associated with obesity and metabolic disorders. 31305461 2019
CUI: C0025517
Disease: Metabolic Diseases
Metabolic Diseases 		0.040 Biomarker group BEFREE Drugs that specifically activate HNF4alpha could be developed for treating metabolic diseases such as diabetes, dyslipidemia and cholestasis, as well as drug metabolism and detoxification. 19239393 2009
CUI: C0025517
Disease: Metabolic Diseases
Metabolic Diseases 		0.040 Biomarker group BEFREE Dysfunction of HNF 4 alpha is associated with metabolic disorders including diabetes. 18184923 2008
CUI: C0025517
Disease: Metabolic Diseases
Metabolic Diseases 		0.040 GeneticVariation group BEFREE In particular, HNF4alpha dysfunction leads to metabolic disorders, including diabetes. 15615695 2005