HOXA1, homeobox A1, 3198

N. diseases: 95; N. variants: 5
Disease: Squamous cell carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.040 AlteredExpression disease BEFREE It is known that HOXA1, which was upregulated in squamous cell carcinomas, affects both cell growth and death. 22864671 2012
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.040 Biomarker disease BEFREE In multivariate analysis, HOXA1 was an independent prognostic factor for OSCC patients (HR: 2.68; 95% CI: 1.59-2.97; p = 0.026). 22498108 2012
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.040 AlteredExpression disease BEFREE The dysplasia tissues showed higher expression of HOXA2, A3, B3, and D10 than normal mucosa tissues whereas they showed lower expression of HOXA1, B7, B9, and C8 than SCC. 17294802 2006
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.040 AlteredExpression disease BEFREE Comparison of HOX gene expressions between adenocarcinoma and squamous cell carcinoma tissues showed higher expressions of HOXA1, D9, D10 and D11 in squamous cell carcinoma tissues than in adenocarcinoma tissues. 16525661 2006