|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Rexin-G is a replication-incompetent retroviral vector displaying a cryptic <i>SIG</i>-binding peptide for targeting abnormal Signature (<i>SIG</i>) proteins in tumors and encoding a dominant-negative human cyclin G1 construct.
|
30705966 |
2019 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Herein, we successfully modified a previous phage display derived Glypican-3 (GPC3) binding peptide (GBP) on the surface of a Fe<sub>3</sub>O<sub>4</sub> Core/Au shell nanocomplex (FANP) to improve GBP binding affinity and enhance FANP tumor photothermal therapy (PTT) efficacy.
|
31603456 |
2019 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Biodistribution of the radiolabeled MMP-14-binding peptide or substrate-binding peptide was determined in mice bearing orthotopic patient-derived xenograft (PDX) glioma tumors by PET imaging.
|
31773232 |
2019 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
To circumvent this, here we employ adeno-associated virus (AAV) gene therapy vectors to express 3TSR alone or in combination with the CD47-binding peptide of TSP-1 and evaluate the impact on tumor development and survival in a mouse model of EOC.
|
31160686 |
2019 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
The 12-mer Clu-binding peptide plays multiple roles in tumor development and metastasis.
|
28076321 |
2017 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Finally, first PET/CT scans of HNSCC and NSCLC patients displayed SFITGv6 accumulation specifically in tumors, but not in inflammatory lesions.<b>Conclusions:</b> Thus, SFITGv6 represents a novel powerful tracer for imaging and possibly for endoradiotherapy of ITGα<sub>v</sub>β<sub>6</sub>-positive carcinoma.<i></i>.
|
28468949 |
2017 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
By combining administration of an engineered mouse serum albumin/IL-2 fusion with an Fc fusion to an integrin-binding peptide (2.5F-Fc), significant survival improvements are achieved in three syngeneic mouse tumor models, including complete responses with protective immunity.
|
28473400 |
2017 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
However, except for serum Hp, the correlation of tumor Hp expression with hepatocellular carcinoma (HCC) progression is still unclear.
|
28158312 |
2017 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Haptoglobin (Hp) is a well-known acute-phase protein that possibly has influence on tumors through the immune response.
|
23563546 |
2013 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Further, we demonstrate that both human glioma and mouse melanoma cells overexpressing Hp showed increased tumor growth.
|
20822092 |
2010 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Haptoglobin (Hp), an acute phase protein that has genetic polymorphism, can influence immune response to tumor.
|
19446743 |
2009 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Recently, fucosylated haptoglobin was identified as a possible tumor marker for pancreatic cancer.
|
18951869 |
2008 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Haptoglobin, alpha1 antitrypsin, and leucine-rich alpha2-glycoprotein were all greatly elevated after tumor resection in PC patients.
|
17414053 |
2007 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Treatment with ATN-161 resulted in a significant decrease in the expression of phosphorylated mitogen-activated protein kinase, microvessel density, and cell proliferation in tumors grown in vivo.
|
16985061 |
2006 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
These studies describe the detection of a haptoglobin species, its characterization as the HPR gene product, and its association with both pregnancy and neoplasia.
|
2465547 |
1989 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Interestingly, an excess of TFC3 and a deficit of the haptoglobin heterozygote, HP2-1, were associated with diploid tumor DNA content and Stage I, particularly in male patients.
|
2917316 |
1989 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Haptoglobin groups were investigated in 309 patients with primary lung cancer divided by sex, smoking habits and tumor type.
|
3759102 |
1986 |