HP, haptoglobin, 3240

N. diseases: 464; N. variants: 9
Disease: Sepsis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0243026
Disease: Sepsis
Sepsis 		0.060 Biomarker disease BEFREE High-level CFH-Hp complexes may impair clearance mechanisms and eliminate Hp's beneficial effect during sepsis. 31639229 2019
CUI: C0243026
Disease: Sepsis
Sepsis 		0.060 Biomarker disease BEFREE Acute phase serum proteins, like Haptoglobin (Hp), have been associated with increased mortality in bacteria mediated acute lung inflammation and sepsis in neonates. 30625342 2019
CUI: C0243026
Disease: Sepsis
Sepsis 		0.060 GeneticVariation disease BEFREE Haptoglobin-2 variant increases susceptibility to acute respiratory distress syndrome during sepsis. 31573976 2019
CUI: C0243026
Disease: Sepsis
Sepsis 		0.060 AlteredExpression disease BEFREE Upregulation of HP was associated with the severity of systemic inflammation and the development of sepsis. 26727089 2016
CUI: C0243026
Disease: Sepsis
Sepsis 		0.060 AlteredExpression disease BEFREE Extremely low expression of Hp may explain the lack of a correlation between Hp phenotype and sepsis in preterm infants. 26344008 2016
CUI: C0243026
Disease: Sepsis
Sepsis 		0.060 Biomarker disease BEFREE In this study, patients with sepsis and systemic inflammatory response syndrome (SIRS) were examined using plasma protein profiling following immunodepletion treatment to remove the most abundant proteins, serum albumin, transferrin, haptoglobin, anti-trypsin, IgG, and IgA. 17081067 2006