Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0038443
Disease: Stress, Psychological
Stress, Psychological
0.030 GeneticVariation disease BEFREE This study aimed to assess whether HSD11B1 genotypes and haplotypes are associated with depression risk, severity of symptoms and suicidal attempts, considering early-life stress as an environmental factor. 31704233 2020
CUI: C0038443
Disease: Stress, Psychological
Stress, Psychological
0.030 AlteredExpression disease BEFREE The impact of early-life stress on corticosteroid carrier protein levels and 11β-hydroxysteroid dehydrogenase 1 expression in adolescent rats. 30831440 2019
CUI: C0038443
Disease: Stress, Psychological
Stress, Psychological
0.030 Biomarker disease BEFREE In this article, we reviewed the role of CRF, pro-opiomelanocortin (POMC)-derived peptides, GCs of the HPA, and 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) in AD, with a discussion of the pathogenetic mechanisms of inflammation and skin barrier functions, including antimicrobial defense, and their association with PS. 29023418 2017