|
Schizophrenia
|
0.380 |
Biomarker
|
disease |
BEFREE |
Our results support previously reported associations between HSPA1A and HSPA1B SNPs and schizophrenia symptomatology.
|
30342847 |
2018 |
|
Schizophrenia
|
0.380 |
AlteredExpression
|
disease |
BEFREE |
A quantitative reverse-transcription PCR study showed that the levels of HSPA1A/1B mRNA, another gene that has been associated with schizophrenia, were significantly suppressed after exogenous ADM treatment.
|
27776076 |
2016 |
|
Schizophrenia
|
0.380 |
Biomarker
|
disease |
PSYGENET |
In this study, we analyzed the potential implication of HSPA1A +190G/C, HSPA1B +1267A/G, and HSPA1L +2437T/C polymorphisms in the susceptibility to paranoid schizophrenia in a homogenous Caucasian Polish population.
|
23893339 |
2014 |
|
Schizophrenia
|
0.380 |
GeneticVariation
|
disease |
BEFREE |
We also identified the CGT haplotype as a risk haplotype for schizophrenia and demonstrated the effects of HSPA1A and HSPA1B genotypes on the psychopathology and age of onset.
|
23893339 |
2014 |
|
Schizophrenia
|
0.380 |
AlteredExpression
|
disease |
LHGDN |
Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia.
|
19165527 |
2009 |
|
Schizophrenia
|
0.380 |
Biomarker
|
disease |
PSYGENET |
We previously investigated a group of single-nucleotide polymorphisms of a set of genes coding for heat shock proteins (HSPA1A, HSPA1B and HSPA1L) and found a significant association between one HSPA1B variation and schizophrenia (SZ).
|
19439993 |
2009 |
|
Schizophrenia
|
0.380 |
GeneticVariation
|
disease |
BEFREE |
We previously investigated a group of single-nucleotide polymorphisms of a set of genes coding for heat shock proteins (HSPA1A, HSPA1B and HSPA1L) and found a significant association between one HSPA1B variation and schizophrenia (SZ).
|
19439993 |
2009 |
|
Schizophrenia
|
0.380 |
Biomarker
|
disease |
BEFREE |
Association between the three polymorphisms of HSP70-1 (HSPA1A), HSP70-hom (HSPA1L) and HSP70-2 (HSPA1B) and schizophrenia has been reported.
|
18299791 |
2008 |
|
Schizophrenia
|
0.380 |
Biomarker
|
disease |
PSYGENET |
Association between the three polymorphisms of HSP70-1 (HSPA1A), HSP70-hom (HSPA1L) and HSP70-2 (HSPA1B) and schizophrenia has been reported.
|
18299791 |
2008 |
|
Schizophrenia
|
0.380 |
Biomarker
|
disease |
BEFREE |
We speculate that the overexpression of SERPINA3, IFITM1, IFITM2, IFITM3, CHI3L1, MT2A, CD14, HSPB1, HSPA1B, and HSPA1A in schizophrenia subjects represents a long-lasting and correlated signature of an early environmental insult during development that actively contributes to the pathophysiology of prefrontal dysfunction.
|
17568569 |
2007 |
|
Schizophrenia
|
0.380 |
Biomarker
|
disease |
PSYGENET |
We speculate that the overexpression of SERPINA3, IFITM1, IFITM2, IFITM3, CHI3L1, MT2A, CD14, HSPB1, HSPA1B, and HSPA1A in schizophrenia subjects represents a long-lasting and correlated signature of an early environmental insult during development that actively contributes to the pathophysiology of prefrontal dysfunction.
|
17568569 |
2007 |
|
Schizophrenia
|
0.380 |
Biomarker
|
disease |
PSYGENET |
There were no significant differences in the allelic or genotype frequencies of the HSPA1A and HSPA1L polymorphisms between the schizophrenia patients and the controls, while there was a marginal difference in the genotype frequency of the HSPA1B polymorphisms, and a significant difference in the allelic frequency of the HSPA1B polymorphisms between the schizophrenia patients and the controls.
|
15963589 |
2005 |
|
Schizophrenia
|
0.380 |
Biomarker
|
disease |
BEFREE |
This study aimed to investigate the association between the three polymorphisms of HSP70-1 (HSPA1A), HSP70-hom (HSPA1L) and HSP70-2 (HSPA1B) and schizophrenia.
|
15963589 |
2005 |
|
Neoplasm Metastasis
|
0.350 |
Biomarker
|
phenotype |
BEFREE |
Tumor-derived exosomes educate dendritic cells to promote tumor metastasis via HSP72/HSP105-TLR2/TLR4 pathway.
|
29209566 |
2017 |
|
Neoplasm Metastasis
|
0.350 |
Biomarker
|
phenotype |
CTD_human |
HSP70 Inhibition Limits FAK-Dependent Invasion and Enhances the Response to Melanoma Treatment with BRAF Inhibitors.
|
26984758 |
2016 |
|
Neoplasm Metastasis
|
0.350 |
Biomarker
|
phenotype |
BEFREE |
Further, a marked reduction in cell migration and invasion was also observed, indicating the potential role of HSP70-2 in metastasis.
|
25213699 |
2014 |
|
Neoplasm Metastasis
|
0.350 |
AlteredExpression
|
phenotype |
BEFREE |
Therefore, DNP mediated HSP70-2 expression may be an important factor of NPC-high metastasis.
|
23667540 |
2013 |
|
Neoplasm Metastasis
|
0.350 |
AlteredExpression
|
phenotype |
BEFREE |
HSP72 and gp96 expression were significantly associated with the presence of tumor infiltration, lymph node and remote metastasis.
|
23266770 |
2013 |
|
Neoplasm Metastasis
|
0.350 |
AlteredExpression
|
phenotype |
BEFREE |
HSP72 and gp96 expression in colonic carcinomas with metastasis was significantly higher than those with non-metastasis (p < 0.05).
|
17464101 |
2007 |
|
Paranoid Schizophrenia
|
0.320 |
GeneticVariation
|
disease |
BEFREE |
The present study aimed to determine whether genetic variants in the HSPA1A (rs1008438, rs562047) and HSPA1L (rs2075800) genes are associated with the risk of paranoid schizophrenia and the clinical presentation of the disease.
|
30342847 |
2018 |
|
Major Depressive Disorder
|
0.320 |
GeneticVariation
|
disease |
BEFREE |
RESULTS Significant associations were found between MDD and interactions among polymorphisms in HSPA1A, SLC6A4, and BDNF or HSPA1A, BDNF, and APOE genes.
|
29703883 |
2018 |
|
Paranoid Schizophrenia
|
0.320 |
GeneticVariation
|
disease |
BEFREE |
In this study, we analyzed the potential implication of HSPA1A +190G/C, HSPA1B +1267A/G, and HSPA1L +2437T/C polymorphisms in the susceptibility to paranoid schizophrenia in a homogenous Caucasian Polish population.
|
23893339 |
2014 |
|
Paranoid Schizophrenia
|
0.320 |
Biomarker
|
disease |
PSYGENET |
Heat shock protein 70 gene polymorphisms are associated with paranoid schizophrenia in the Polish population.
|
23893339 |
2014 |
|
Malignant neoplasm of prostate
|
0.320 |
Biomarker
|
disease |
BEFREE |
Ultrasound targeted microbubble destruction for novel dual targeting of HSP72 and HSC70 in prostate cancer.
|
24606454 |
2014 |
|
Kidney Failure, Acute
|
0.320 |
Biomarker
|
disease |
BEFREE |
Accordingly, urinary Hsp72 was significantly increased in patients with clinical AKI before serum creatinine elevation.
|
21204265 |
2011 |