Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.380 Biomarker disease BEFREE Our results support previously reported associations between HSPA1A and HSPA1B SNPs and schizophrenia symptomatology. 30342847 2018
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.380 AlteredExpression disease BEFREE A quantitative reverse-transcription PCR study showed that the levels of HSPA1A/1B mRNA, another gene that has been associated with schizophrenia, were significantly suppressed after exogenous ADM treatment. 27776076 2016
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.380 Biomarker disease PSYGENET In this study, we analyzed the potential implication of HSPA1A +190G/C, HSPA1B +1267A/G, and HSPA1L +2437T/C polymorphisms in the susceptibility to paranoid schizophrenia in a homogenous Caucasian Polish population. 23893339 2014
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.380 GeneticVariation disease BEFREE We also identified the CGT haplotype as a risk haplotype for schizophrenia and demonstrated the effects of HSPA1A and HSPA1B genotypes on the psychopathology and age of onset. 23893339 2014
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.380 AlteredExpression disease LHGDN Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia. 19165527 2009
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.380 Biomarker disease PSYGENET We previously investigated a group of single-nucleotide polymorphisms of a set of genes coding for heat shock proteins (HSPA1A, HSPA1B and HSPA1L) and found a significant association between one HSPA1B variation and schizophrenia (SZ). 19439993 2009
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.380 GeneticVariation disease BEFREE We previously investigated a group of single-nucleotide polymorphisms of a set of genes coding for heat shock proteins (HSPA1A, HSPA1B and HSPA1L) and found a significant association between one HSPA1B variation and schizophrenia (SZ). 19439993 2009
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.380 Biomarker disease BEFREE Association between the three polymorphisms of HSP70-1 (HSPA1A), HSP70-hom (HSPA1L) and HSP70-2 (HSPA1B) and schizophrenia has been reported. 18299791 2008
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.380 Biomarker disease PSYGENET Association between the three polymorphisms of HSP70-1 (HSPA1A), HSP70-hom (HSPA1L) and HSP70-2 (HSPA1B) and schizophrenia has been reported. 18299791 2008
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.380 Biomarker disease BEFREE We speculate that the overexpression of SERPINA3, IFITM1, IFITM2, IFITM3, CHI3L1, MT2A, CD14, HSPB1, HSPA1B, and HSPA1A in schizophrenia subjects represents a long-lasting and correlated signature of an early environmental insult during development that actively contributes to the pathophysiology of prefrontal dysfunction. 17568569 2007
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.380 Biomarker disease PSYGENET We speculate that the overexpression of SERPINA3, IFITM1, IFITM2, IFITM3, CHI3L1, MT2A, CD14, HSPB1, HSPA1B, and HSPA1A in schizophrenia subjects represents a long-lasting and correlated signature of an early environmental insult during development that actively contributes to the pathophysiology of prefrontal dysfunction. 17568569 2007
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.380 Biomarker disease PSYGENET There were no significant differences in the allelic or genotype frequencies of the HSPA1A and HSPA1L polymorphisms between the schizophrenia patients and the controls, while there was a marginal difference in the genotype frequency of the HSPA1B polymorphisms, and a significant difference in the allelic frequency of the HSPA1B polymorphisms between the schizophrenia patients and the controls. 15963589 2005
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.380 Biomarker disease BEFREE This study aimed to investigate the association between the three polymorphisms of HSP70-1 (HSPA1A), HSP70-hom (HSPA1L) and HSP70-2 (HSPA1B) and schizophrenia. 15963589 2005