HTN1, histatin 1, 3346

N. diseases: 19; N. variants: 0
Disease: Diabetes Mellitus, Non-Insulin-Dependent ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.020 Biomarker disease BEFREE Abbreviations BBB blood-brain barrier CDC25B cell division cycle 25 homolog B CYP2D6 Cytochrome P450 2D6 binding DCCM dynamic cross-correlation map DS Discovery Studio H bond hydrogen bond HIA human intestinal absorption LAR leukocyte antigen-related phosphatase MD molecular dynamics MEG-2 maternal-effect germ-cell defective 2 MM-PBSA molecular mechanics Poisson Boltzmann surface area) PCA principal component analysis PDB Protein Data Bank pNPP p-nitrophenyl phosphate PPB plasma protein binding PTP1B protein tyrosine phosphotase 1B RMSD root mean square deviation RMSF root mean square fluctuation SHP-1 src homologous phosphatase-1 SHP-2 src homologous phosphatase-2 SPC single-point charge TCPTP T cell protein tyrosine phosphatase T2DM Type 2 diabetes mellitus VDW van der Waals Communicated by Ramaswamy H. Sarma. 31490104 2019
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.020 Biomarker disease BEFREE Compared with the reference BMI group (18·5-22·9 kg/m2), they had an increased PR for HTN (1·55-1·77) and T2DM (1·54-1·93). 28112066 2017