HTR1A, 5-hydroxytryptamine receptor 1A, 3350

N. diseases: 229; N. variants: 9
Disease: Mood Disorders ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0525045
Disease: Mood Disorders
Mood Disorders 		0.400 GeneticVariation group BEFREE Gene-gene interaction studies suggest that the 5-HT1A receptor G(-1019) allele is a risk allele which could be used as a marker for depression and related mood disorders. 18639564 2008
CUI: C0525045
Disease: Mood Disorders
Mood Disorders 		0.400 Biomarker group PSYGENET Altered regulation of the serotonin-1A (5-HT1A) receptor gene is implicated in major depression and mood disorders. 22232550 2012
CUI: C0525045
Disease: Mood Disorders
Mood Disorders 		0.400 GeneticVariation group BEFREE History of mood disorders and HTR1A G allele variation, the C-1019G polymorphism of the transcriptional control region of the 5-HT1A receptor, independently predicted the incidence of IFN-induced depression in HCV patients, whether separately or jointly considered and although not reciprocally associated. 26001668 2015
CUI: C0525045
Disease: Mood Disorders
Mood Disorders 		0.400 Biomarker group PSYGENET RGS6 is enriched in hippocampal and cortical neurons, 5-HT(1A)R-expressing cells implicated in mood disorders. 24421401 2014