HTR1D, 5-hydroxytryptamine receptor 1D, 3352

N. diseases: 26; N. variants: 1
Disease: Anorexia Nervosa ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003125
Disease: Anorexia Nervosa
Anorexia Nervosa 		0.040 GeneticVariation disease BEFREE We investigated the association of 25 single nucleotide polymorphisms (SNPs), capturing 71-91% of the common variance in candidate genes, stathmin (STMN1), serotonin receptor 1D (HTR1D), tryptophan hydroxylase 2 (TPH2) and brain-derived neurotrophic factor (BDNF), with AN and EDs characterized by regular SV. 20946355 2011
CUI: C0003125
Disease: Anorexia Nervosa
Anorexia Nervosa 		0.040 GeneticVariation disease BEFREE We confirmed that common single-nucleotide polymorphisms (SNPs) within OPRD1 (rs533123, P=0.0015) confer risk for AN, and obtained suggestive evidence that common SNPs near HTR1D (rs7532266, P=0.04) confer risk for restricting-type AN specifically. 21079607 2011
CUI: C0003125
Disease: Anorexia Nervosa
Anorexia Nervosa 		0.040 GeneticVariation disease BEFREE Further evidence of association of OPRD1 & HTR1D polymorphisms with susceptibility to anorexia nervosa. 16806108 2007
CUI: C0003125
Disease: Anorexia Nervosa
Anorexia Nervosa 		0.040 Biomarker disease LHGDN Candidate genes for anorexia nervosa in the 1p33-36 linkage region: serotonin 1D and delta opioid receptor loci exhibit significant association to anorexia nervosa. 12740597 2003
CUI: C0003125
Disease: Anorexia Nervosa
Anorexia Nervosa 		0.040 Biomarker disease BEFREE The combined statistical genetic evidence suggests that HTR1D and OPRD1 or linked genes may be involved in the etiology of AN. 12740597 2003