HTR1F, 5-hydroxytryptamine receptor 1F, 3355

N. diseases: 20; N. variants: 2
Disease: Alzheimer's Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.040 Biomarker disease BEFREE The 5-HT-6 receptor antagonists Idalopirdine and Intepirdine have shown the most progress in current clinical trials and warrant consideration as emerging treatments for AD. 28253832 2017
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.040 GeneticVariation disease BEFREE In conclusion, the association of ApoE epsilon4 to AD in a sample of patients from the Basque Country is confirmed, though the association to C267T polymorphism of the 5-HT(6) receptor has not been observed. 12618306 2003
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.040 GeneticVariation disease BEFREE Our result suggests that the 267C allele of the 5-HT(6) receptor gene may not be a genetic risk factor for AD. 12023056 2002
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.040 GeneticVariation disease BEFREE The difference in the 5-HT(6) genotype or allele distributions between the AD patients with depressive disorders (n = 25) and those without (n = 120) was not significant. 11442897 2001