IAPP, islet amyloid polypeptide, 3375

N. diseases: 183; N. variants: 3
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020459
Disease: Hyperinsulinism
Hyperinsulinism
0.020 Biomarker disease BEFREE In vivo, Plasma glucose, triglyceride, rIAPP and insulin increased in T2DM rats compared with the control group. 29523142 2018
CUI: C0020459
Disease: Hyperinsulinism
Hyperinsulinism
0.020 Biomarker disease BEFREE We conclude that exogenous E2 administered to male mice may block human IAPP-mediated beta-cell loss both by direct action on beta-cells and by decreasing insulin demand through inhibition of weight gain or increasing insulin action. 12086946 2002