|
Hypertensive disease
|
0.200 |
Biomarker
|
group |
BEFREE |
Factors independently associated with higher mean low-density lipoprotein cholesterol and apolipoprotein B were female gender, older age, higher education, higher income, obesity, and hypertension.
|
31809516 |
2019 |
|
Hypertensive disease
|
0.200 |
Biomarker
|
group |
BEFREE |
Those with remission of hypertension had a significant weight loss (p < 0.001), decrease in body mass index (p < 0.001), 24-h total systolic BP (p = 0.047), baPWV (p = 0.042), triglycerides (p = 0.049) and apolipoprotein B/apolipoprotein A1 (p = 0.004), and an increase in high-density lipoprotein cholesterol (p < 0.001) at 1 year.
|
30317431 |
2019 |
|
Hypertensive disease
|
0.200 |
AlteredExpression
|
group |
BEFREE |
In clinics, patients with PDD suffered less hypertension and had lower serum low-density lipoprotein cholesterol and apolipoprotein B levels when compared to the other patients with PD.
|
30233306 |
2018 |
|
Hypertensive disease
|
0.200 |
GeneticVariation
|
group |
BEFREE |
This study shows the relevance of polymorphisms in APOB (odds ratio (OR), 1.17; 95% confidence interval (95% CI), 0.74-1.85), APOC3 (OR, 1.33; 95% CI, 0.82-2.17) and APOE (OR, 1.75; 95% CI, 1.09-2.80), as genetic risk markers for hypercholesterolemia; polymorphisms in ACE (OR, 1.68; 95% CI, 0.32-8.77) and AGT (OR, 1.74; 95% CI, 0.97-3.14) for hypertension; and in APOE*3/*4 (OR, 2.06; 95% CI, 1.70-2.51) and APOE*4/*4 (OR, 3.08; 95% CI, 1.85-5.12) as unambiguous markers of dementia.
|
29081697 |
2017 |
|
Hypertensive disease
|
0.200 |
Biomarker
|
group |
BEFREE |
Additionally, in the hypertension group, TT carriers showed a higher tendency of serum triglyceride (P = 0.069) and significantly higher apolipoprotein B (P = 0.015) and smaller low-density lipoprotein (LDL) particle size (P < 0.001) than either TC or CC subjects.
|
29208002 |
2017 |
|
Hypertensive disease
|
0.200 |
Biomarker
|
group |
BEFREE |
Sex- and Obesity-specific Association of Aromatase (CYP19A1) Gene Variant with Apolipoprotein B and Hypertension.
|
26415088 |
2015 |
|
Hypertensive disease
|
0.200 |
Biomarker
|
group |
BEFREE |
The children of mothers with GH had higher BP compared to the reference group (SBP percentage difference 2.7 (95% CI 1.6, 3.8); DBP 3.4 (2.1, 4.6); MAP 3.1 (2.0, 4.1), P < 0.001 for all) and a tendency towards higher cholesterol and apolipoprotein B values.
|
23354981 |
2013 |
|
Hypertensive disease
|
0.200 |
GeneticVariation
|
group |
BEFREE |
Among the polymorphisms genotyped, we identified eight genes (CNTNAP2, LEPR, CRHR1, NTAN1, SLC12A3, ALPL, BGLAP, and APOB) containing variants that were associated with hypertension (chi2 P values 0.002-0.048), several of which interact with the hypothalamus-pituitary-adrenal axis.
|
18496130 |
2008 |
|
Hypertensive disease
|
0.200 |
Biomarker
|
group |
BEFREE |
Multivariate analyses revealed moderate subgroup differences, with older participants having a larger decrease in LDL cholesterol and apolipoprotein B levels compared with younger participants (p <0.001), women having larger increases in HDL than men (p <0.01), nonsmokers having larger decreases in LDL and triglyceride levels compared with smokers (p <0.05), those with hypertension having smaller decreases in apolipoprotein B than those without hypertension (p <0.05), and those with a larger waist circumference having a diminished lowering of triglycerides in response to treatment with simvastatin (p <0.01).
|
16516587 |
2006 |
|
Hypertensive disease
|
0.200 |
GeneticVariation
|
group |
BEFREE |
These results suggest that ACE Ins/Del polymorphism is associated with hypertension, and APOB EcoRI polymorphism is associated with LDL-C variation in Afro-Brazilians.
|
15543563 |
2004 |
|
Hypertensive disease
|
0.200 |
AlteredExpression
|
group |
BEFREE |
We enrolled 94 patients with hypertension and 102 healthy controls in this study and determined their plasma levels of triglyceride, total cholesterol, high- and low-density lipoprotein-cholesterol, apolipoprotein AI, and apolipoprotein B.
|
12624708 |
2003 |
|
Hypertensive disease
|
0.200 |
GeneticVariation
|
group |
BEFREE |
The association of the A640G gene variation with the presence and extent of CAD was not only identified in the total sample, but was even stronger in various high risk subpopulations of younger individuals (e.g. with hypertension with or without increased apolipoprotein B plasma levels).
|
10488959 |
1999 |
|
Hypertensive disease
|
0.200 |
Biomarker
|
group |
BEFREE |
Smoking, apolipoprotein B and history of hypertension were found to be independent predictors of CAD and MI.
|
9693941 |
1998 |
|
Hypertensive disease
|
0.200 |
Biomarker
|
group |
HPO |
|
|
|