ICAM1, intercellular adhesion molecule 1, 3383

N. diseases: 737; N. variants: 18
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0042164
Disease: Uveitis
Uveitis
0.220 AlteredExpression disease BEFREE Our results suggested that GC31 suppressed LPS-mediated ICAM-1 expression by inhibiting the activation of NF-κB and partially by attenuating the activity of ERK1/2 and p38 MAPK in vascular endothelium, which may contribute to ameliorating vascular inflammatory diseases, such as uveitis. 23401649 2013
CUI: C0042164
Disease: Uveitis
Uveitis
0.220 GeneticVariation disease BEFREE G/R 241 polymorphism of intercellular adhesion molecule 1 (ICAM-1) is associated with Fuchs uveitis. 20445114 2010
CUI: C0042164
Disease: Uveitis
Uveitis
0.220 Therapeutic disease RGD Monoclonal antibodies against CD54 (ICAM-1) and CD11a (LFA-1) prevent and inhibit endotoxin-induced uveitis. 7641842 1995