GADL1, glutamate decarboxylase like 1, 339896

N. diseases: 192; N. variants: 16
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.090 Biomarker disease BEFREE ADC, mainly ADC<sub>oscillating</sub> , increased in the group of nodules with intermediate malignancy (ADC<sub>pulsed</sub> : 0.75 ± 0.25 × 10<sup>-3</sup> mm<sup>2</sup> /s vs. 0.64 ± 0.07 × 10<sup>-3</sup> mm<sup>2</sup> /s in benign nodules, P = 0.025; ADC<sub>oscillating</sub> : 0.81 ± 0.20 × 10<sup>-3</sup> mm<sup>2</sup> /s vs. 0.65 ± 0.13 × 10<sup>-3</sup> mm<sup>2</sup> /s, P = 0.0008) and ADC<sub>pulsed</sub> decreased in the group of progressed hepatocellular carcinomas (ADC<sub>pulsed</sub> : 0.60 ± 0.08 × 10<sup>-3</sup> mm<sup>2</sup> /s, P = 0.042; ADC<sub>oscillating</sub> : 0.68 ± 0.08 × 10<sup>-3</sup> mm<sup>2</sup> /s, P = 0.1). 31507025 2020
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.090 Biomarker disease BEFREE Pre-operative ADC predicts early recurrence of HCC after curative resection. 30027408 2019
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.090 Biomarker disease BEFREE • The optimal cutoff values of ADC, D, D*, and f for predicting recurrence in HBV associated HCC were 0.858 × 10<sup>-3</sup> mm<sup>2</sup>/s, 0.985 × 10<sup>-3</sup> mm<sup>2</sup>/s, 12.5 × 10<sup>-3</sup> mm<sup>2</sup>/s, and 23.4%, respectively. 30972544 2019
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.090 Biomarker disease BEFREE Multivariate analysis revealed that reverse target sign on hepatobiliary phase in FNHs (p = 0.009), iso or hyperintensity on ADC map in FNHs and HCAs (p = 0.009, < 0.001, respectively), central hypointensity on arterial phase in NETs (p = 0.001), hepatobiliary target sign in ICCs (p = 0.002), the presence of septum and capsule in HCCs (all p < 0.001) were significant independent features of each tumor group over other tumor groups. 31134313 2019
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.090 Biomarker disease BEFREE Prediction of hepatocellular carcinoma response to <sup>90</sup>Yttrium radioembolization using volumetric ADC histogram quantification: preliminary results. 31142363 2019
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.090 GeneticVariation disease BEFREE The proposed fusion of deep features derived from logb0, logb100, and logb600 with deeply supervised loss function generated the highest accuracy for HCC grading (80%), thus outperforming the method of deep feature derived from the ADC map directly (72.5%), the original b0 (65%), b100 (68%), and b600 (70%) images. 31169907 2019
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.090 Biomarker disease BEFREE In patients with two HCC lesions, highly similar ADC values for the two HCC lesions may be a preoperative predictor of MVI. 29392365 2018
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.090 Biomarker disease BEFREE In general ADC values can help discriminate between AE and hepatocellular carcinoma and intrahepatic cholangiocarcinoma. 29110943 2018
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.090 AlteredExpression disease BEFREE Our data show that an extended panel of immunohistochemical markers can reclassify around 60% of LCCs as ADC or SQCC. 22031317 2011