|
Acute cerebral ischemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
BLXW7, as a ligand of integrin αvβ3, may be able to effectively localize the anti-oxidant CeNPs to the ischemic penumbra region, which may provide more adequate opportunities for CeNPs to exert anti-oxidative stress effects and subsequently reduce apoptosis in acute cerebral ischemia/reperfusion.
|
30074164 |
2018 |
|
Acute Cerebrovascular Accidents
|
0.100 |
Biomarker
|
disease |
BEFREE |
Protecting the ischaemic penumbra as an adjunct to thrombectomy for acute stroke.
|
29674752 |
2018 |
|
Acute Cerebrovascular Accidents
|
0.100 |
Biomarker
|
disease |
BEFREE |
Early molecular oxidative stress biomarkers of ischemic penumbra in acute stroke.
|
31455665 |
2019 |
|
Acute Cerebrovascular Accidents
|
0.100 |
Biomarker
|
disease |
BEFREE |
The Frequency of Substantial Salvageable Penumbra in Thrombectomy-ineligible Patients with Acute Stroke.
|
30010229 |
2018 |
|
Acute Cerebrovascular Accidents
|
0.100 |
Biomarker
|
disease |
BEFREE |
Penumbra detection in acute stroke with perfusion magnetic resonance imaging: Validation with <sup>15</sup> O-positron emission tomography.
|
30937950 |
2019 |
|
Acute Cerebrovascular Accidents
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We suggest that up-regulation of FGF-2 is one of the mechanisms that leads to angiogenesis and neuro-protection in the penumbra region after acute stroke in man.
|
16132618 |
2005 |
|
Acute Cerebrovascular Accidents
|
0.100 |
Biomarker
|
disease |
BEFREE |
These include the genetic factors in the aetiology and treatment of ischaemic stroke, the interplay between microvessels, neurons and glia (i.e., the microvascular unit) in the setting of acute stroke, a critical review of various neuroimaging techniques to visualize ischaemic tissue that is still viable (the ischaemic penumbra), recanalization strategies by means of intravenous thrombolysis as well as future recanalization techniques by, for example, intra-arterial or mechanical thrombolysis and sonothrombolysis by a transcranial approach.
|
20175862 |
2010 |
|
Acute Cerebrovascular Accidents
|
0.100 |
Biomarker
|
disease |
BEFREE |
A multiparametric MRI protocol was performed at 4.7T to characterize brain damage within three region of interest: 'LesionD0' (diffusion), 'Mismatch' representing penumbra (perfusion/diffusion) and 'Hypoxia' (voxels < 40% of StO<sub>2</sub> within the region of interest LesionD0).
|
27466373 |
2017 |
|
Acute Cerebrovascular Accidents
|
0.100 |
Biomarker
|
disease |
BEFREE |
The target of acute stroke therapy is that portion of the ischemic region that is still potentially salvageable, i.e. the ischemic penumbra.
|
16651816 |
2006 |
|
Acute Cerebrovascular Accidents
|
0.100 |
Biomarker
|
disease |
BEFREE |
It is challenging to revitalize ischemic penumbra after an acute stroke with intracranial perfusion insufficiency.
|
31344491 |
2019 |
|
Acute Cerebrovascular Accidents
|
0.100 |
Biomarker
|
disease |
BEFREE |
Author Correction: Protecting the ischaemic penumbra as an adjunct to thrombectomy for acute stroke.
|
30742037 |
2019 |
|
Acute Cerebrovascular Accidents
|
0.100 |
Biomarker
|
disease |
BEFREE |
Collateral blood flow is known to be an important factor that sustains the penumbra during acute stroke.
|
30803332 |
2019 |
|
Acute Cerebrovascular Accidents
|
0.100 |
Biomarker
|
disease |
BEFREE |
A plethora of studies have demonstrated the efficacy of NBO on the penumbra in acute stroke.
|
30936686 |
2019 |
|
Adult Diffuse Large B-Cell Lymphoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
TSPAN33 is expressed in several lymphomas including Hodgkin's and Diffuse large B cell lymphoma.
|
24211713 |
2013 |
|
Adult Oligodendroglioma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Some cells from the oligodendroglioma grade III tumor proper shared molecular characteristics with the cells from the penumbra of the same tumor suggesting that a subpopulation of cells within the oligodendroglioma grade III tumor consisted of normal brain cells.
|
25249434 |
2015 |
|
Androgen-Insensitivity Syndrome
|
0.030 |
Biomarker
|
disease |
BEFREE |
In lieu of head-to-head randomized control trials, we performed an adjusted indirect treatment comparison (ITC) meta-analysis to assess the comparative efficacy and safety of different METs, Solitaire+IVtPA and Penumbra+IVtPA in AIS patients.
|
29513676 |
2018 |
|
Androgen-Insensitivity Syndrome
|
0.030 |
Biomarker
|
disease |
BEFREE |
Penumbra/infarct growth beyond the initial penumbra is involved in the unexplained END in AIS patients receiving reperfusion therapy.
|
31485869 |
2020 |
|
Androgen-Insensitivity Syndrome
|
0.030 |
Biomarker
|
disease |
BEFREE |
Assessment of collateral circulation and penumbra area during pre-treatment imaging within an appropriate time-window prior to thrombolytic therapy will therefore improve the identification of AIS patients who may benefit from thrombolysis treatment.
|
29399075 |
2018 |
|
Anemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Penumbra(-/-) mice develop massive splenomegaly, basophilic macrocytic red blood cells, and anemia as they age.
|
17158226 |
2007 |
|
Angiogenic Switch
|
0.010 |
Biomarker
|
disease |
BEFREE |
We hypothesize that SSS extraction is an angiogenic switch in penumbra post-stroke, and corresponding mechanisms are investigated.
|
29895489 |
2018 |
|
Atrial Fibrillation
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
We describe here a case presentation of acute RAE secondary to atrial fibrillation treated successfully with Penumbra Indigo Aspiration System, a novel device in peripheral endovascular interventions.
|
29554859 |
2018 |
|
Autoimmune Diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
We conclude that TSPAN33 may be used as a diagnostic biomarker or as a target for therapeutic antibodies for treatment of certain B cell lymphomas or autoimmune diseases.
|
24211713 |
2013 |
|
B-Cell Lymphomas
|
0.010 |
Biomarker
|
group |
BEFREE |
We conclude that TSPAN33 may be used as a diagnostic biomarker or as a target for therapeutic antibodies for treatment of certain B cell lymphomas or autoimmune diseases.
|
24211713 |
2013 |
|
Basilar artery occlusion
|
0.010 |
Biomarker
|
disease |
BEFREE |
Conclusion and Relevance: Multimodal endovascular therapy using the Penumbra system and stent retriever demonstrated a high recanalization rate and favorable outcomes for BAO.
|
28848166 |
2017 |
|
Brain Infarction
|
0.020 |
Biomarker
|
disease |
BEFREE |
Hyperlipidemia dose-dependently attenuated vascular endothelial growth factor-induced capillary formation and pericyte coverage of brain endothelial cells, abolishing the improvement of cerebral blood flow during subsequent stroke, resulting in the loss of the metabolic penumbra and increased brain infarction.
|
23559636 |
2013 |