|
Ischemic stroke
|
0.100 |
Biomarker
|
disease |
BEFREE |
The SPECT/CT-based assessment procedure of the volume of the penumbra may serve as an effective selecting tool when HBOT is administered for patients with ischemic stroke.
|
31846850 |
2020 |
|
Ischemic stroke
|
0.100 |
Biomarker
|
disease |
BEFREE |
Intraperitoneal delivery of acetate-encapsulated liposomal nanoparticles for neuroprotection of the penumbra in a rat model of ischemic stroke.
|
30936698 |
2019 |
|
Ischemic stroke
|
0.100 |
Biomarker
|
disease |
BEFREE |
In this study, we investigate the relationship of T2'/R2' with dynamic susceptibility contrast-based relative cerebral blood flow (rCBF) in acute ischemic stroke to assess their plausibility as surrogate markers of the ischemic penumbra.
|
28929836 |
2019 |
|
Ischemic stroke
|
0.100 |
Biomarker
|
disease |
BEFREE |
In a transgenic mouse model with an enhanced susceptibility to ischemic stroke, we found a more pronounced discrimination in sodium/potassium ratios between penumbra and healthy regions.
|
30705295 |
2019 |
|
Ischemic stroke
|
0.100 |
Biomarker
|
disease |
BEFREE |
The primary aim of this study was to evaluate the correlation between the areas of infarction and penumbra on CTP scans and functional outcome in patients with AIS.METHODSThis was a retrospective review of 100 consecutively treated patients with acute anterior circulation ischemic stroke who underwent CT angiography (CTA) and CTP at admission between February 2011 and October 2014.
|
30641833 |
2019 |
|
Ischemic stroke
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Frontline contact aspiration thrombectomy using SOFIA catheter for acute ischemic stroke: period-to-period comparison with Penumbra catheter.
|
31037498 |
2019 |
|
Ischemic stroke
|
0.100 |
Biomarker
|
disease |
BEFREE |
Post-stroke neuroinflammation contributes to the pathophysiology of ischemic stroke in the acute phase through damaging neurons in the penumbra region.
|
31297748 |
2019 |
|
Ischemic stroke
|
0.100 |
Biomarker
|
disease |
BEFREE |
Molecular signature of penumbra in acute ischemic stroke: a pilot transcriptomics study.
|
31020007 |
2019 |
|
Ischemic stroke
|
0.100 |
Biomarker
|
disease |
BEFREE |
Ischemic penumbra is the main therapeutic target for acute ischemic stroke.
|
31099185 |
2019 |
|
Ischemic stroke
|
0.100 |
Biomarker
|
disease |
BEFREE |
Dendritic and synaptic plasticity in the penumbra are important processes and are considered to be therapeutic targets of ischemic stroke.
|
30552877 |
2019 |
|
Ischemic stroke
|
0.100 |
Biomarker
|
disease |
BEFREE |
Animal models of ischaemic stroke and characterisation of the ischaemic penumbra.
|
28923277 |
2018 |
|
Ischemic stroke
|
0.100 |
Biomarker
|
disease |
BEFREE |
In this study, we have used synchrotron-based X-ray fluorescence imaging to visualize the elemental changes in undamaged, penumbra, and infarct brain tissue, following ischemic stroke.
|
29370523 |
2018 |
|
Ischemic stroke
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Ischemic stroke decreased Trx-1 activity but not the expression in penumbra tissue.
|
30447684 |
2018 |
|
Ischemic stroke
|
0.100 |
Biomarker
|
disease |
BEFREE |
The authors report on a patient presenting with acute ischemic stroke from a tandem ICA and MCA occlusion with penumbra.
|
29148900 |
2018 |
|
Ischemic stroke
|
0.100 |
Biomarker
|
disease |
BEFREE |
Mechanical endovascular therapy for acute ischemic stroke: An indirect treatment comparison between Solitaire and Penumbra thrombectomy devices.
|
29513676 |
2018 |
|
Ischemic stroke
|
0.100 |
Biomarker
|
disease |
BEFREE |
Optimal thresholds for ischemic penumbra predicted by computed tomography perfusion in patients with acute ischemic stroke treated with mechanical thrombectomy.
|
28600481 |
2018 |
|
Ischemic stroke
|
0.100 |
Biomarker
|
disease |
BEFREE |
Advanced understanding of ischaemic stroke pathophysiology supports an individualized approach to patient evaluation, given variance in the rate of ischaemic core progression and the extent of salvageable penumbra.
|
28727192 |
2018 |
|
Ischemic stroke
|
0.100 |
Biomarker
|
disease |
BEFREE |
In the physiopathological chain of ischemic stroke, brain edema is one first element that if attended to might reduce tissue necrosis, penumbra, and increase functional recovery.
|
28523299 |
2017 |
|
Ischemic stroke
|
0.100 |
Biomarker
|
disease |
BEFREE |
Our results demonstrate that in the post-ischemic penumbra, a tight temporal correlation exists between the angiogenic markers α5β1 and Ang1 and the TJPs, suggesting a potential role for Ang1 and α5β1 in promoting BBB integrity following ischemic stroke.
|
28864200 |
2017 |
|
Ischemic stroke
|
0.100 |
Biomarker
|
disease |
BEFREE |
Validation of MRI Determination of the Penumbra by PET Measurements in Ischemic Stroke.
|
27879370 |
2017 |
|
Ischemic stroke
|
0.100 |
Biomarker
|
disease |
BEFREE |
In this article describing how reperfusion regimes have evolved along different paths for STEMI and for ischemic stroke, a new concept is made that in STEMI infarct lead Q waves can be the counterpart of the "core" and ST elevation the "penumbra".
|
27846459 |
2017 |
|
Ischemic stroke
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
An Increase of Sigma-1 Receptor in the Penumbra Neuron after Acute Ischemic Stroke.
|
28687423 |
2017 |
|
Ischemic stroke
|
0.100 |
Biomarker
|
disease |
BEFREE |
Here we show for the first time that treatment with TRC051384 significantly reduces stroke associated neuronal injury (87% reduction in area of penumbra recruited to infarct, and 25% reduction in brain edema) and disability in a rat model of transient ischemic stroke even when administered 8 hours post onset of ischemia.
|
21167846 |
2011 |
|
Ischemic stroke
|
0.100 |
Biomarker
|
disease |
BEFREE |
These include the genetic factors in the aetiology and treatment of ischaemic stroke, the interplay between microvessels, neurons and glia (i.e., the microvascular unit) in the setting of acute stroke, a critical review of various neuroimaging techniques to visualize ischaemic tissue that is still viable (the ischaemic penumbra), recanalization strategies by means of intravenous thrombolysis as well as future recanalization techniques by, for example, intra-arterial or mechanical thrombolysis and sonothrombolysis by a transcranial approach.
|
20175862 |
2010 |
|
Ischemic stroke
|
0.100 |
Biomarker
|
disease |
BEFREE |
Our previous work has demonstrated that angiogenesis occurs in the damaged brain tissue of patients surviving acute ischaemic stroke and increased microvessel density in the penumbra is associated with longer patient survival.
|
16132618 |
2005 |