IFI27, interferon alpha inducible protein 27, 3429

N. diseases: 332; N. variants: 4
Disease: Malignant transformation ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1608408
Disease: Malignant transformation
Malignant transformation 		0.030 Biomarker phenotype BEFREE Skp2-dependent proteasomal degradation of p27 plays role in the malignant transformation of CCA. 25663461 2015
CUI: C1608408
Disease: Malignant transformation
Malignant transformation 		0.030 Biomarker phenotype BEFREE In this article, we review the literature concerning the role of p27 in Barrett's esophagus and its malignant transformation, and we evaluate its possible role as an important clinical biomarker, as well as potential chemopreventive clinical agents aimed at substituting its antitumoral activity. 15230722 2004
CUI: C1608408
Disease: Malignant transformation
Malignant transformation 		0.030 AlteredExpression phenotype BEFREE We conclude that pituitary adenomas show a lower level of p27 protein expression than the normal cells from which they are derived, with malignant transformation leading to complete loss of p27 immunoreactivity. 10523037 1999